Description
The ZytoLight ® SPEC ERBB2/CEN 17 Dual Color Probe is designed for the detection of ERBB2 (a.k.a HER2) gene amplification frequently observed in solid malignant neoplasms e.g. breast cancer samples.
Amplification of the proto-oncogene ERBB2, observed in approximately 20% of all breast cancer samples, has been correlated with a poor prognosis of the disease. In addition, detection of ERBB2 amplification by FISH may help in selecting patients eligible for ERBB2-targeted therapy.
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