Description
D2-40 antibody is a selective marker of lymphatic endothelium in normal tissues and vascular lesions. Studies have shown [D2-40] staining in lymphatic channel endothelium, but not in the adjacent capillary. In the same study, D2-40 stained endothelium of lymphangiomas; whereas hemangiomas, glomus tumors, angiolipomas, pyogenic granulomas and vascular malformations were negative for staining. D2-40 has also been shown to react with Kaposi’s sarcoma and a subset of angiosarcomas. Studies indicate that D2-40 may be a very specific marker for malignant mesothelioma.
SPECIFICATIONS
Specifications
| INTENDED USE | IVD |
|---|---|
| SPECIES REACTIVITY | Human, Mouse, Rat |
| SOURCE | Mouse Monoclonal |
| CLONE | D2-40 |
| ISOTYPE | IgG1 |
| ANTIGEN | 0-linked sialoglycoprotein |
| LOCALIZATION | Cytoplasm (lymphatic epithelium) |
| POSITIVE CONTROL | Breast or colon cancer |
DATASHEETS & SDS
| Download Data Sheet |
| Download RUO Data Sheet for International |
| Download SDS Sheet |
Regulatory Notice: Biocare’s IVD-labeled products comply with US-FDA and European IVDD regulation. Other regions may have additional requirements for such labeling, please contact your local distributor.
ONCORE PROTOCOL
| ANTIBODY | DOWNLOAD |
|---|---|
| Download Oncore Protocol |
REFERENCES
1. Kahn HJ, et al. Lab Invest. 2002 Sep; 82(9):1255-7.
2. Chu AY, et al. Mod Pathol. 2005 Jan; 18(1):105-10.
3. Rao P, et al. Am J Dermatopathol. 2013 Jun; 35(4):432-7.
4. Kao SC, et al. Pathology. 2011 Jun; 43(4):313-7.
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