Cytokeratin 5/6

Description

Studies have shown Cytokeratin 5/6 antibody reacts with human epidermis and non-keratinizing epithelium. It has also been shown to react with cytokeratin 6, weakly with cytokeratin 4, and does not react with cytokeratins 1, 7, 8, 10, 13, 14, 18 and 19. CK5/6 has been shown to express in the vast majority of squamous cell carcinoma, basal cell carcinomas, thymomas, salivary gland tumors, and mesothelioma. It rarely reacts with pulmonary adenocarcinomas.

SPECIFICATIONS

Specifications

INTENDED USE IVD
SPECIES REACTIVITY Human
SOURCE Mouse Monoclonal
CLONE CK5/6.007
ISOTYPE IgG1
ANTIGEN CK5/6
LOCALIZATION Cytoplasmic
POSITIVE CONTROL Prostate or skin
DATASHEETS & SDS
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Regulatory Notice: Biocare’s IVD-labeled products comply with US-FDA and European IVDD regulation. Other regions may have additional requirements for such labeling, please contact your local distributor.

REFERENCES

1. Ordonez NG. Am J Surg Pathol. 1998 Oct; 22(10):1215-21.
2. Chu P, Weiss LM. Mod Pathol. 2002 Jan; 15(1):6-10.
3. Aquiar FN, et al. Clinics (Sao Paulo). 2013 May; 68(5):638-43.

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