Ki-67 (R)

Ki-67 [SP6] is a rabbit monoclonal antibody that is intended for laboratory use in the qualitative identification of Ki-67 protein by immunohistochemistry (IHC) in formalin-fixed paraffin-embedded (FFPE) human tissues. The clinical interpretation of any staining or its absence should be complemented by morphological studies using proper controls and should be evaluated within the context of the patient’s clinical history and other diagnostic tests by a qualified pathologist. The Ki-67 nuclear antigen is associated with cell proliferation. It is found throughout the cell cycle in the G1, S, G2, and M phases; but not the (GO) phase. It is used to grade proliferation rates of tumors. The high affinity and/or binding capacity of rabbit antibodies provide superior staining results and less chance for technical false negatives.

Specifications

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3. Rossi S, et al. A comparative study between a novel category of immunoreagents and the corresponding mouse monoclonal antibodies. Am J Clin Pathol 2005; 124(2): 295-302.
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5. Gibbons D, et al. Comparison of topoisomerase II alpha and MIB-1 expression in uterinecervical squamous lesions. Mod Pathol 1997 May; 10 (5): 409-413.
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7. Clinical and Laboratory Standards Institute (CLSI). Protection of Laboratory workers from occupationally Acquired Infections; Approved guideline-Third Edition CLSI document M29-A3 Wayne, PA 2005